https://ojwatson.co.uk/tags/diagnostics/diagnosticsSource Themes Academic (https://sourcethemes.com/academic/)en-us© 2026 OJ WatsonMon, 16 Feb 2026 00:00:00 +0000https://ojwatson.co.uk/img/headers/newyork.jpghttps://ojwatson.co.uk/tags/diagnostics/https://ojwatson.co.uk/2026/02/16/nature-medicine-pfhrp23-risk/Mon, 16 Feb 2026 00:00:00 +0000https://ojwatson.co.uk/2026/02/16/nature-medicine-pfhrp23-risk/<p>A key recent output is our <strong>Nature Medicine (2025)</strong> paper on the global risk of selection and spread of <em>Plasmodium falciparum</em> pfhrp2/3 deletions.</p> <ul> <li>Paper: <a href="https://doi.org/10.1038/S41591-025-03974-3">https://doi.org/10.1038/S41591-025-03974-3</a></li> <li>Related modelling background: <a href="https://doi.org/10.7554/eLife.25008">eLife 2017 pfhrp2 deletion modelling</a></li> <li>Related software: <a href="https://ojwatson.co.uk/project/hrp2malaria/">hrp2malaRia</a> and <a href="https://ojwatson.co.uk/project/hrpup/">hrpup</a></li> </ul> <p>This work builds on several years of modelling, surveillance, and policy-facing analysis around malaria rapid diagnostic test performance. The central question is an operational one: where and when might pfhrp2/3 deletions undermine diagnosis, and how should surveillance adapt?</p> <p>The paper links directly to my broader <a href="https://ojwatson.co.uk/research/#malaria-transmission-modelling">Malaria research</a> and WHO-facing policy support activities.</p>